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Inert gas inside the pump creates pressure on the expandable reservoir, pushing medication into the internal tubing.

Specifically, this prescription medication is used to treat spasticity caused by conditions such as multiple sclerosis, spinal cord injury or disease, or cerebral palsy.

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For generalized spasticity, the panel listed diazepam as probably effective and tizanidine as possibly effective, although insufficient data exist regarding motor function and side-effect profile.

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Effects of constraint-induced movement therapy on spasticity in patients with hemiparesis after stroke.

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Treatment may be restarted at the initial continuous infusion rate and titrated accordingly.

One factor that is thought to be related to spasticity is the stretch reflex.

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Please read the following important safety information about ITB Therapy.

Females must be postmenopausal for at least one year, surgically sterile, or practicing an effective method of birth control before entry and throughout the study; have a negative urine pregnancy test at each visit.

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GABAB agonists such as baclofen have been shown to attenuate the self-administration of cocaine, heroin, alcohol and nicotine (see Cousins et al.

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Have patient report immediately to prescriber signs of withdrawal (high fever, mental changes, increased spasm, or muscle rigidity), loss of strength and energy, severe dizziness, passing out, illogical thinking, fatigue, polyuria, behavioral changes, seizures, vision changes, angina, muscle pain, burning or numbness feeling, signs of breathing problems (shortness of breath, wheezing, coughing, or breathing gets worse), urinary retention, change in amount of urine passed, blood in urine, mood changes, hallucinations, abnormal movements, twitching, change in balance, dysphagia, difficulty speaking, involuntary eye movements, or arrhythmia (HCAHPS).

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During the following visits, patients were asked to report in detail their consumption of alcohol, their craving for alcohol (similar, decreased, or no longer present), their compliance to treatment (doses of baclofen taken), the side-effects of the treatment, their smoking habits, and the use of other psychotropic drugs.

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The catheter through which the pump delivers the baclofen into his spinal fluid has failed twice, requiring two surgeries to fix it and an additional laminectomy to make more room around his spine.

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Recent research has also found that certain medications are effective against tinnitus in the animal model.

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