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The side-effects far outweigh the benefits for me. It took about 5 weeks for the good effects to kick in - and when they did, I felt like a huge boulder had been lifted off of my chest, I could cope with things much better. However, the nausea is still present, even though it's been two months since I started. What's frightening is the blurred vision. My vision started getting blurry not long after I started Pristiq, and it has become worse. It has gotten to the point where the words I'm typing are now blurry and the laptop is less than two feet away from my face. Am weaning myself off of this and have an appointment with my doctor next week. Too bad... I was hopeful about this one.



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My wife is prone to depressive disorders and we have wasted a lot of time on different doctors and medications that turned out to be useless and full of shit. She is easy at getting depressed with anything - bad weather, untasty coffee, loud music - anything could turn her into a miserable wreck or what is still worse into an aggressive creature. Luckily we have visited a new doctor last month and he put her on Pristiq. This medication definitely helps. She can control her behavior and the reactions she develops in response to trivial things. I think Pristiq will help her get ultimate control over her emotions.

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This is of course person subjective, so it's best to talk it through with your GP first rather then requesting an increase.

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My doc wants to put me on as it has less side effects than Effexor (which I hate esp the sweats) has told me to just stop the Effexor and start taking 100mg of Pristiq the next day.

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This work was supported by the National Institute of Neurological Disorders and Stroke and the National Institute on Aging of the National Institutes of Health NIH, grant numbers K23NS089922, UL1RR024992, KL2TR000450, K08NS079405, P01NS074969m P01AG03991, P01AG026276, K01AG053425 and P50AG05681.

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